A professor of psychiatry adds to the discussion about sex-change. Possibly the most notable addition from the scientific community. From his view, the debate around sex-change is one of mental disorder vs. social conditioning, of psychiatry vs. psychology. It's a long read but with some interesting perspectives.
"As for the adults who came to us claiming to have discovered their “true” sexual identity and to have heard about sex-change operations, we psychiatrists have been distracted from studying the causes and natures of their mental misdirections by preparing them for surgery and for a life in the other sex. We have wasted scientific and technical resources and damaged our professional credibility by collaborating with madness rather than trying to study, cure, and ultimately prevent it."